come on guys..
pulmonary fibrosis causing drugs?busulfan,bleomycin,methotrexate
SLE like syndrome is caused by?hydralazine,isoniazid,procainamide
drug that causes reactivation of TB?etanercept
drug causing crystalluria?acyclovir
drugs causing redistribution of fat from extremeties to the trunk?protease inh.,glucocortecoids
drug causing livedoreticularis?amantadine
drug which may result in production of dysphonia?oral cortecosteroids

Respiratory Alkalosis? Mild Aspinirn toxicity..
Purple Toe Syndrome? Warfarin toxicity

more for Rx-induced SLE: Phenytoin, Sulfasalazine, D-Penicillamine

eosinopenia----glucocortecoid therapy
ticlopidine------neutropenia

don',t forget Amiodarone for pul.

fibrosis which may lead to death in 15% pt.

& Methotrexate for crystalluria

also mitomycin c and methysergide cause pulm.fibrosis
pancreatitis-----valproate,didanosine and zalcitabine

Hemostat,
what book are you using for pharm.

I didn',t even know that Methotrexate can cause Pul Fibrosis.

Thanks in advance.

Also, if we gonna a little extreme and add D-Penicillamine as of the drugs causing Lupus then might as well know all the following too: :)

Besides HIPP, the following can cause drup induced Lupus: (from Wikipedia)

o Clindamycin (antibiotic)
o Pyrazinamide (antibiotic)
o Quinidine (antiarrhythmic)
o D-Penicillamine (anti-inflammatory)
o Carbamazepine (anticonvulsant)
o Oxcarbazepine (anticonvulsant)
o Infliximab (immunosuppressant)
o Propafenone (antiarrhythmic)



From E-medicine, heres the full fledged list :

Drugs that cause drug-induced lupus erythematosus are as follows:

* Acebutolol
* Amiodarone
* Bupropion
* Captopril
* Carbamazepine
* Chlorpromazine
* Diltiazem
* Docetaxel
* Ethosuximide
* Gemfibrozil
* Glyburide
* Gold salt
* Griseofulvin
* Hydantoins
* Hydralazine
* Hydroxychloroquine
* Interferons
* Interleukins
* Isoniazid
* Leuprolide acetate
* Lithium
* Lovastatin
* Mephenytoin
* Methyldopa
* Minocycline
* Nitrofurantoin
* Olanzapine
* Ophthalmic timolol
* Oral contraceptives
* Penicillamine
* Phenytoin
* Practolol
* Procainamide
* Propylthiouracil
* Quinidine
* Reserpine
* Rifampin
* Sertraline2
* Simvastatin
* Sulfasalazine
* Tetracycline
* Ticlopidine
* Tiotropium bromide inhaler
* Trimethadione
* Tumor necrosis factor (TNF)3
* Valproate
* Voriconazole

Drugs that cause flares of SLE are as follows:

* Cimetidine
* Hydralazine
* Hydrochlorothiazide
* Mesantoin
* P -Aminobenzoic acid (PABA)
* Penicillin
* Phenylbutazone
* Sulfonamides
* Terbinafine

TCA',s Cardiotoxic
Risperidone hyperprolactinemia
Clozapine Siezues n Agranulocytosis